Vitamin E succinate has been found to inhibit tumor growth and enhance the effectiveness of immunotherapy by targeting ...
High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
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Study identifies vitamin E succinate as key to tumor growth controlHigh levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing ...
Merck Sharp & Dohme LLC patents report the development of proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase (Von Hippel-Lindau disease tumor suppressor [VHL] ligands) ...
Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.
First, that hybrid ubiquitin chains containing several linkage types play critical roles in regulating innate immune signalling networks; second that the essential roles of TRAF6 in initiating innate ...
and attachment to the substrate protein by ubiquitin ligases (E3s). USP14 regulates PERIOD (PER) protein stability post-translationally in Drosophila via interaction with SLIMB, a protein involved ...
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom ...
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