The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 ...

The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park.

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

City, county and state officials are preparing for whatever the weather system has in store for Western New York.

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

Milano practiced without a red non-contact jersey for the first time since his bicep injury in August and was listed on the ...

Around 10:50 p.m., Route 20A, also known as Big Tree Road, will convert to two-lane, one-way traffic eastbound away from the ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

The NFL opened up voting for the 2024 NFL Pro Bowl this week. With six games to go, several Bills players could either join ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...