The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park.

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

City, county and state officials are preparing for whatever the weather system has in store for Western New York.

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

Milano practiced without a red non-contact jersey for the first time since his bicep injury in August and was listed on the ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

The NFL opened up voting for the 2024 NFL Pro Bowl this week. With six games to go, several Bills players could either join ...

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

Buffalo Bills cornerback Rasul Douglas was in the treatment room on Wednesday with linebacker Matt Milano when something occurred to him. “I was just telling him in the Epsom salt bath, like bro, can ...

Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.