George Kittle will lead the San Francisco 49ers into their game versus the Buffalo Bills at Highmark Stadium on Sunday at ...

Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Around 10:50 p.m., Route 20A, also known as Big Tree Road, will convert to two-lane, one-way traffic eastbound away from the ...

The highly anticipated Buffalo Bills clash against the San Francisco 49ers, scheduled for Sunday at Highmark Stadium, faces ...

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

The Buffalo Bills Sunday night game against the San Francisco 49ers is shaping up to be a weather game as bitter cold air ...

The Bills and 49ers play Sunday, Dec. 1 at 8:20 p.m. at Highmark Stadium in Orchard Park. The game will be broadcast on local NBC affiliates, including WHEC Channel 10 in Rochester. The game will be ...