Coleman has not practiced since injuring his wrist, and he was ruled out for Buffalo's Week 11 clash against the Kansas City Chiefs the preceding Monday. His Wednesday return to practice (albeit in a limited capacity) and as-of-now undetermined Week 13 status are, thus, encouraging signs.

Coach McDermott shared the injury report at his first weekly news conference before the 49ers game. Dalton Kincaid will not be practicing, and Keon Coleman and Spencer Brown will be limited in the week.

Tight end Dalton Kincaid was held out with a knee injury Wednesday as the Bills returned to practice following their bye week. Right tackle Spencer Brown (ankle) and rookie receiver Keon Coleman (wrist) were limited participants after missing Buffalo’s most recent victory against Kansas City in Week 11.

Coleman was hurt near the end of Sunday’s win over the Miami Dolphins, suffering a wrist injury on a late hit from Dolphins safety Jordan Poyer. The team announced on Friday that Coleman had been ruled out for Sunday’s game, with head coach Sean McDermott saying there is a chance he will miss significantly more time beyond this week.

The latest updates on Keon Coleman’s injury status for Week 11 vs. the Kansas City Chiefs. Stay informed with our comprehensive injury news and current updates.

San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa and cornerback Charvarius Ward - and was clobbered 38-10 by the Green Bay Packers on Sunday. NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

Several injury updates stemmed from Wednesday's Bills practice, including reports on three significant contributors who were held out of Buffalo's Week 11 matchup with the Kansas City

Coach McDermott shared the injury report at his first weekly news conference before the 49ers game. Dalton Kincaid will not be practicing, and Keon Coleman and Spencer Brown will be limited in the week.