The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled ...

Before you make any Week 13 NFL picks, be sure to see the exact NFL score predictions from SportsLine expert Eric Cohen.

The Buffalo Bills activated linebacker Matt Milano off injured reserve, and he's expected to play Sunday against the San ...

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the week inside Highmark Stadium. With a lake-effect storm advisory already in ...

The Game Matchups Preview series is dedicated to breaking down how the Buffalo Bills match up with their opponent in every ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

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According to Travis Kelce's brother, Jason Kelce, not too many folks thought that the ball would end up in Allen's hands at ...

Chargers (-2.5) at 6-5 Falcons, Sunday 1:00 p.m. ET, CBS (Kevin Harlan and Trent Green) L.A. makes the short-week trip to ...

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with ...