Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

San Francisco 49ers offensive tackle Trent Williams was seen in the locker room on Wednesday using a scooter as he recovers ...

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

The 49ers have revealed their latest injury report before their Sunday Night Football tilt against the Buffalo Bills.

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

49ers linebacker Fred Warner revealed Wednesday that he has played most of this season with a fracture in his ankle. Warner ...

Head coach Kyle Shanahan explains why the 49ers don't rotate their running backs to give Christian McCaffrey a breather.

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

San Francisco 49ers star Fred Warner told reporters Wednesday that he fractured an ankle on Oct. 29 and has been receiving ...