1Department of Oncology, Mayo Clinic, Rochester, Minnesota.

President Donald Trump has issued a number of executive orders (EO) focused on healthcare for people who identify as lesbian, gay, bisexual, transgender, queer, or other sexual or gender minority.

Cancer Grand Challenges, Cancer Research UK, London, United Kingdom.

Copyright held by the owner/author(s).

Cancer Discov (2025) 15 (3): 656.

Major Finding: Multiple oncogenic fusion kinases converge on GUK1 to augment GTP synthesis and promote lung cancer growth. Concept: ALK phosphorylates the GDP-synthesizing enzyme GUK1 at tyrosine 74 ...

1Department of Medicine, Cedars-Sinai Medical Center, Cedars-Sinai Cancer Institute, Los Angeles, California. 2Department of Biomedical Sciences, Cedars-Sinai Medical Center, Cedars-Sinai Cancer ...

Most anti-PD1/PD-L1 antibodies have exhibited poor efficacy in some clinical indications, primarily due to insufficient infiltration of immune cells into the tumor microenvironment (TME). This study ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California.

1Department of Medicine, Columbia Center for Human Development, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York. 2Herbert Irving Comprehensive ...