More information: Béatrice Roche et al, A Salmonella subset exploits erythrophagocytosis to subvert SLC11A1-imposed iron deprivation, Cell Host & Microbe (2025). DOI: 10.1016/j.chom.2025.04.013 ...

Studies of cell wall lipopolysaccharide (LPS) biosynthesis in Salmonella typhimurium have led to the isolation of a number of mutants which are defective in enzymes catalysing different synthetic ...

When the infection is over, some of the cells specific to that pathogen remain as memory cells, waiting to be called rapidly into service again if the same threat returns. In the mouse model of ...

Chong, A., et al. (2021) Cytosolic replication in epithelial cells fuels intestinal expansion and chronic fecal shedding of Salmonella Typhimurium. Cell Host & Microbe. doi. org/ 10. 1016/ j. chom ...

Therefore, to survive and replicate, bacteria must act rapidly to avoid this pathway to degradation. Salmonella, the bacterium that causes food poisoning and typhoid fever, can do that.

Salmonella infections, which can feature food poisoning, disrupt these electric fields because they damage the cells, which alerts the body’s immune cells to come and clean up the mess.

The findings, published in Cell Host & Microbe, shed new light on the survival strategies of Salmonella Typhimurium ST313, which causes thousands of deaths each year in sub-Saharan Africa.

Story at a glance Researchers sent human cells to the International Space Station. In parallel experiments in space and on the ground, some cells were infected with salmonella.

Cytosolic replication in epithelial cells fuels intestinal expansion and chronic fecal shedding of Salmonella Typhimurium. Cell Host & Microbe, 2021; DOI: 10.1016/j.chom.2021.04.017 ...