There is increased risk for major gastrointestinal bleeding with edoxaban vs VKA therapy in patients with atrial fibrillation following TAVR.

Cite this: A Case of Obscure Gastrointestinal Bleeding Secondary to a Small Bowel Gastrointestinal Stromal Tumor Detected by Magnetic Resonance Enterography - Medscape - Nov 18, 2008.

It found overall GI bleeding incidence to be 0.45%, defined as 'GI blood loss requiring a transfusion, prolonged hospital stay and/or a drop in hemoglobin greater than 3 g/dl'.

Those with stage 5 CKD had a 40% higher chance of being hospitalized with gastrointestinal (GI) bleeding than patients without CKD (aOR 1.4, 95% CI 1.3-1.4, P <0.001), reported Mingyue He, MD, of ...

Currently hospitalized patients (dubbed "inpatients") with upper GI bleeding showed a significantly higher mortality rate at 6 weeks than patients hospitalized for GI bleeding alone (dubbed ...

Researchers also noted consistent associations between lower GI bleeding risk and apixaban vs. rivaroxaban among patients receiving the standard dose (HR = 0.72; 95% CI, 0.64-0.82), those ...

“Anything out of the ordinary, like a GI bleed, can extend a case, which delays the next patient and could delay the rest of the day’s cases too. That may result in overtime for staff.” Dr. Saeed ...

The adjusted odd ratios for gastrointestinal bleeding leading to hospitalization or death for any cinacalcet use, current use, and past use were 1.04, 0.97, and 1.22, respectively, with no use as ...

Acute upper GI bleeding has an incidence of 84–160 cases per 100,000 individuals annually, with a 10% mortality rate. Peptic ulcers, variceal bleeding, and mucosal erosions are among the most ...

DEAR DR. ROACH: I am 87 and have been jogging/running for 35 years. I recently had a major upper-gastrointestinal bleed after collapsing and losing consciousness. The problem was found and corrected.