Prince Frederik of Luxembourg Dies at 22 of Rare Disease He Led Foundation to Research
P rince Frederik of Luxembourg, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, died in Paris at age 22 on March 1—a day after Rare Disease Day—of a rare genetic disease known as POLG.
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What is the rare genetic disorder that claimed Luxembourg prince’s life at 22?
Prince Frederik of Luxembourg died on March 1, 2025, at the age of 22 after a prolonged battle with POLG mitochondrial disease — a rare genetic disorder that causes progressive multi-organ failure. Diagnosed at 14,
A young member of the Luxembourg royal family has passed away from a rare genetic disorder affecting his mitochondria.
"It is with a very heavy heart that my wife and I would like to inform you of the passing of our son, The POLG Foundation ...
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